AKR1B1 抗体
Quick Overview for AKR1B1 抗体 (ABIN6936373)
抗原
See all AKR1B1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length AKR1B1 protein
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亚型
- IgG1 kappa
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anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 1-316) antibody
AKR1B1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) antibodyAKR1B1 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal CPTC-AKR1B1-3 unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 1-316) antibodyAKR1B1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 102-135) antibodyAKR1B1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14877 unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 114-230) antibodyAKR1B1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 1-316) antibodyAKR1B1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 1-316) antibodyAKR1B1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 228-316) antibodyAKR1B1 适用: 人, 大鼠, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 290-316), (C-Term) antibodyAKR1B1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14692 unconjugated
anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (AA 287-316), (C-Term) antibodyAKR1B1 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL),Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: 293T, HEK293, A431, HeLa, HepG2, MOLT4, Jurkat and Raji whole cell lysates, Human Kidney, Human colon carcinoma tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
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别名
- AKR1B1
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背景
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AKR1B1, Aldehyde reductase, aldehyde reductase 1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), Aldose reductase, AR, Lii5-2 CTCL tumor antigen, low Km aldose reductase,Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker)
Cellular localisation: Cytoplasmic -
分子量
- 37kDa
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基因ID
- 231, 521212
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UniProt
- P15121
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途径
- Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
抗原
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