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Recombinant Iba1 抗体 (AA 1-146)

This anti-Iba1 antibody is a 小鼠 单克隆 antibody detecting Iba1 in IHC (f). Suitable for 人.
产品编号 ABIN6936371
发货至: 中国

Quick Overview for Recombinant Iba1 抗体 (AA 1-146) (ABIN6936371)

抗原

See all Iba1 (IBA1) 抗体
Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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  • 79
单克隆

标记

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This Iba1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

RAIF1-1909
  • 抗原表位

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    AA 1-146

    特异性

    AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Lymph Node, Tonsil or Kidney.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

    别名

    AIF1

    背景

    Allograft inflammatory factor 1 (AIF1), balloon angioplasty responsive transcription (BART1), IBA1, Interferon responsive transcript 1, Ionized calcium-binding adapter molecule 1, IRT1, Microglia response factor (MRF1),AIF1 / Iba1 (Microglia Marker)
    Cellular localisation: Cytoplasmic and Cell Surface

    分子量

    17kDa

    基因ID

    199, 76364

    UniProt

    P55008

    途径

    Smooth Muscle Cell Migration
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