Iba1 抗体 (AA 1-146)
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- 抗原 See all Iba1 (IBA1) 抗体
- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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抗原表位
- AA 1-146
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Iba1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Purified fragment of human recombinant AIF1 protein (around aa 1-146) (exact sequence is proprietary)
- 克隆位点
- AIF1-1909
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IBA1 Primary Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Lymph Node, Tonsil or Kidney.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
- 别名
- AIF1 (IBA1 产品)
- 别名
- AIF-1 antibody, IBA1 antibody, IRT-1 antibody, IRT1 antibody, AI607846 antibody, D17H6S50E antibody, G1 antibody, Iba1 antibody, Bart1 antibody, iba1 antibody, mrf-1 antibody, fa04b11 antibody, wu:fa04b11 antibody, AIF antibody, AIF1 antibody, aif1 antibody, allograft inflammatory factor 1 antibody, AIF1 antibody, Aif1 antibody, aif1 antibody
- 背景
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Allograft inflammatory factor 1 (AIF1), balloon angioplasty responsive transcription (BART1), IBA1, Interferon responsive transcript 1, Ionized calcium-binding adapter molecule 1, IRT1, Microglia response factor (MRF1),AIF1 / Iba1 (Microglia Marker)
Cellular localisation: Cytoplasmic and Cell Surface - 分子量
- 17kDa
- 基因ID
- 199, 76364
- UniProt
- P55008
- 途径
- Smooth Muscle Cell Migration
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