ACTN2 抗体 (AA 557-692)
Our Local Distributor
北京 101111
Quick Overview for ACTN2 抗体 (AA 557-692) (ABIN6936359)
抗原
See all ACTN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 557-692
-
特异性
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
-
交叉反应 （详细）
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- A recombinant fragment (aa557-692) of human ACTN2 protein (exact sequence is proprietary)
-
亚型
- IgG2b kappa
-
-
anti-Actinin, alpha 2 (ACTN2) antibody
ACTN2 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 1-254) antibodyACTN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3293 unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3292 unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3291 unconjugated
anti-Actinin, alpha 2 (ACTN2) (N-Term) antibodyACTN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 1-250) antibodyACTN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (N-Term) antibodyACTN2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) antibodyACTN2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) antibodyACTN2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Known_Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Skeletal or Cardiac Muscle.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- ACTN2 (Actinin, alpha 2 (ACTN2))
-
别名
- ACTN2
-
背景
-
Actin binding protein, Alpha actinin skeletal muscle, isoform 2, CMD1AA, F-actin cross-linking protein,Sarcomeric Actinin Alpha 2 / ACTN2
Cellular localisation: Cytoplasmic -
分子量
- 103kDa
-
基因ID
- 88, 498178
-
UniProt
- P35609
-
途径
- Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
抗原
-
