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Glypican 3 抗体 (AA 511-580) (CF®555)

This anti-Glypican 3 antibody is a 小鼠 单克隆 antibody detecting Glypican 3 in IF, FACS, IHC 和 StM. Suitable for 人.
产品编号 ABIN6934330
发货至: 中国

Quick Overview for Glypican 3 抗体 (AA 511-580) (CF®555) (ABIN6934330)

抗原

See all Glypican 3 (GPC3) 抗体
Glypican 3 (GPC3)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Glypican 3 antibody is conjugated to CF®555

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

SPM595
  • 抗原表位

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    AA 511-580

    纯化方法

    Purified by Protein A/G

    免疫原

    A recombinant fragment containing amino acids 511-580 of human glypican-3

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: 293T cells. Hepatocellular carcinoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Glypican 3 (GPC3)

    别名

    GPC3

    背景

    Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100 % in follicular carcinoma and 70 % in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

    分子量

    67kDa

    基因ID

    2719

    UniProt

    P51654

    途径

    Glycosaminoglycan Metabolic Process
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