HIV-1 p24 抗体 (CF®488A)
Quick Overview for HIV-1 p24 抗体 (CF®488A) (ABIN6933792)
抗原
See all HIV-1 p24 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant HIV-1 Gag p24 protein
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亚型
- IgG1 kappa
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应用备注
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Positive Control: HIV-1 infected cells. Tissues.
Known Application: Immunocytochemistry (Acetone or paraformaldehyde fixed) (1:50-1:100),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 100 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))
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别名
- Human Immunodeficiency Virus Type-1 p24 (HIV1-p24)
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物质类
- Viral Protein
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背景
- Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.
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分子量
- 24kDa (mature), 55kDa & 41kDa (precursors)
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基因ID
- 155348
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UniProt
- P04585
抗原
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