VPS35 抗体 (Biotin)
Quick Overview for VPS35 抗体 (Biotin) (ABIN6932944)
抗原
See all VPS35 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Ubiquitous. Highly expressed in brain, colon, heart, kidney, ovary, placenta, skeletal muscle, small intestine, testis, thymus.,Detects ~92 kDa.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Full length recombinant human VSP35
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亚型
- IgG1
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应用备注
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- WB (1:1000)
- ICC/IF (1:200)
- IP (1:200)
- optimal dilutions for assays should be determined by the user.
- optimal dilutions for assays should be determined by the user.
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说明
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A 1:1000 dilution of ABIN6932944 was sufficient for detection of VPS35 in 10 μg of SH-SY5Y by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- VPS35 (Vacuolar Protein Sorting 35 (VPS35))
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别名
- VPS35
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背景
- Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson's Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).
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基因ID
- 55737
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NCBI登录号
- NP_060676
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UniProt
- Q96QK1
抗原
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