CNTF Receptor alpha 抗体 (AA 151-160)
Quick Overview for CNTF Receptor alpha 抗体 (AA 151-160) (ABIN687637)
抗原
See all CNTF Receptor alpha (CNTFR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-160
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CNTFR Alpha
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination." in: PLoS ONE, Vol. 10, Issue 8, pp. e0133680, (2015) (PubMed).
: "
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Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination." in: PLoS ONE, Vol. 10, Issue 8, pp. e0133680, (2015) (PubMed).
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- CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
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别名
- CNTF Receptor alpha
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背景
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Synonyms: Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha, CNTFR
Background: CNTF Receptor alpha is a receptor belonging to the cytokine superfamily of receptors. Along with LIFR and gp130, CNTF Receptor alpha forms the heterotrimeric CNTF receptor complex. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. During signal transduction, CNTF first binds to CNTF Recepror alpha, and this permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
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基因ID
- 1271
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UniProt
- P26992
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途径
- JAK/STAT Signaling, Feeding Behaviour
抗原
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