Cathepsin L 抗体 (AA 71-170) (Biotin)
Quick Overview for Cathepsin L 抗体 (AA 71-170) (Biotin) (ABIN687534)
抗原
See all Cathepsin L (CTSL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-170
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交叉反应
- 人, Pig, 大鼠
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse capsin L1 proprotein
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
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别名
- Cathepsin L
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背景
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Synonyms: fs, MEP, nkt, Ctsl1, 1190035F06Rik, Cathepsin L1, Cathepsin L, Major excreted protein, p39 cysteine proteinase, Ctsl
Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
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基因ID
- 13039
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UniProt
- P06797
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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