BIN1 抗体 (AA 101-200)
Quick Overview for BIN1 抗体 (AA 101-200) (ABIN687232)
抗原
See all BIN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-200
-
预测反应
- Human,Mouse,Rat,Dog,Cow,Horse
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human BIN1
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- BIN1 (Bridging Integrator 1 (BIN1))
-
别名
- BIN1
-
背景
-
Synonyms: Amphiphysin like protein, AMPH 2, AMPH2, Amphiphysin 2, Amphiphysin II, Amphiphysin like protein, amphiphysin-like, AMPHL, Box Dependant MYC Interacting Protein 1, Bridging Integrator 1, DKFZp547F068, MGC10367, MGC105358, Myc box dependent interacting protein 1, SH3P9, BIN1_HUMAN.
Background: The identification and analysis of tumor suppressors is of major importance for improved diagnosis and treatment of tumors. Bin1 (Box-dependent myc interacting protein 1, also known as SH3P9, amphiphysin II and amphl/amphiphysin-like) is a novel protein that has features of a tumor suppressor. Bin1 interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Bin1 also interacts with HCV NS5A through its SH3 domain.
-
基因ID
- 274
抗原
-