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EPOR 抗体 (AA 301-450)

Cited in 2+ publications. This anti-EPOR antibody is a 兔 多克隆 antibody detecting EPOR in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN686347
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EPOR 抗体 (AA 301-450) (ABIN686347)

抗原

EPOR (Erythropoietin Receptor (EPOR))

适用

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人, 大鼠, 小鼠

宿主

  • 102
  • 28
  • 4
  • 2
  • 2
  • 1

克隆类型

  • 108
  • 30
  • 1
多克隆

标记

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This EPOR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
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    • 1
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    • 1
    • 1
    • 1
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    • 1
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    AA 301-450

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EPOR

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Li, Chen, Shao, Tang, Chen, Chen, Xu: "Oxidative stress induces the decline of brain EPO expression in aging rats." in: Experimental gerontology, Vol. 83, pp. 89-93, (2016) (PubMed).

    Zhong, Zhang: "Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations." in: Molecular medicine reports, Vol. 15, Issue 1, pp. 228-234, (2016) (PubMed).

  • 抗原

    EPOR (Erythropoietin Receptor (EPOR))

    别名

    EPOR

    背景

    Synonyms: EPO-R, Erythropoietin receptor, EPOR

    Background: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

    基因ID

    2057

    UniProt

    P19235

    途径

    JAK/STAT Signaling
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