ITGAV/ITGB5 抗体
This 兔 多克隆 antibody specifically detects ITGAV/ITGB5 in FACS, IF (cc), IF (p), ELISA, IHC (fro) 和 IHC (p). It exhibits reactivity toward 人 和 小鼠. It has been mentioned in 3+ publications
(3 references)
产品编号 ABIN685372
发货至:
中国
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中国
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Quick Overview for ITGAV/ITGB5 抗体 (ABIN685372)
抗原
ITGAV/ITGB5
(Integrin alpha V, Integrin beta 5 (ITGAV/ITGB5))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This ITGAV/ITGB5 antibody is un-conjugated
应用范围
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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交叉反应
- 人, 小鼠
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预测反应
- Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Integrin beta 5 and Integrin alpha V
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis." in: Bone research, Vol. 5, pp. 17008, (2017) (PubMed).
: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).
: "The relationship between the cyclic-RGDfK ligand and ?v?3 integrin receptor." in: Biomaterials, Vol. 34, Issue 26, pp. 6249-60, (2013) (PubMed).
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: "Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis." in: Bone research, Vol. 5, pp. 17008, (2017) (PubMed).
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- ITGAV/ITGB5 (Integrin alpha V, Integrin beta 5 (ITGAV/ITGB5))
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别名
- Integrin Alpha V + Beta 5
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背景
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Synonyms: CD51, MSK8, VNRA, VTNR, Integrin alpha-V, Vitronectin receptor subunit alpha, ITGAV
Background: The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
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基因ID
- 3685
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UniProt
- P06756
抗原
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