CEBPA 抗体 (pSer21)
Quick Overview for CEBPA 抗体 (pSer21) (ABIN683548)
抗原
See all CEBPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer21
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预测反应
- Human,Mouse,Rat,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human CDBP alpha around the phosphorylation site of Ser21
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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别名
- CEBP alpha
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背景
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Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch 5, C/EBP alpha, CAP4, Caspase 8 precursor, CCAAT Enhancer Binding Protein alpha, CEBP, CEBP A, CEBP alpha, CEBPA, FADD homologous ICE/CED 3 like protease, FADD like ICE, FLICE, ICE like apoptotic protease 5, ICE8, MACH, MCH5, MORT1 associated CED 3 homolog, CEBPA_HUMAN.
Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Mutations in this gene are frequently found in acute myeloid leukemia (AML).
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基因ID
- 1050
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途径
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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