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CEBPA 抗体 (pSer21)

This anti-CEBPA antibody is a 兔 多克隆 antibody detecting CEBPA in ELISA, IF (cc), IF (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN683548
发货至: 中国

Quick Overview for CEBPA 抗体 (pSer21) (ABIN683548)

抗原

See all CEBPA 抗体
CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

适用

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宿主

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克隆类型

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多克隆

标记

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This CEBPA antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer21

    预测反应

    Human,Mouse,Rat,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human CDBP alpha around the phosphorylation site of Ser21

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

    别名

    CEBP alpha

    背景

    Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch 5, C/EBP alpha, CAP4, Caspase 8 precursor, CCAAT Enhancer Binding Protein alpha, CEBP, CEBP A, CEBP alpha, CEBPA, FADD homologous ICE/CED 3 like protease, FADD like ICE, FLICE, ICE like apoptotic protease 5, ICE8, MACH, MCH5, MORT1 associated CED 3 homolog, CEBPA_HUMAN.

    Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Mutations in this gene are frequently found in acute myeloid leukemia (AML).

    基因ID

    1050

    途径

    Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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