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B-Cell Linker 抗体 (pTyr96) (Biotin)

Name: B-Cell Linker 抗体 (pTyr96) (Biotin)
SKU: ABIN683460
Availability: OutOfStock

This anti-B-Cell Linker antibody is a 兔多克隆 antibody detecting B-Cell Linker in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.

产品编号 ABIN683460

发货至: 中国

Quick Overview for B-Cell Linker 抗体 (pTyr96) (Biotin) (ABIN683460)

抗原

See all B-Cell Linker (BLNK) 抗体

B-Cell Linker (BLNK)

适用

人

宿主

兔

克隆类型

多克隆

标记

This B-Cell Linker antibody is conjugated to Biotin

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product BLNK Primary Antibody

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pTyr96

交叉反应

人

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human BLNK around the phosphorylation site of Tyr96 [DS(p-Y)EP]

亚型

IgG
anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated

anti-B-Cell Linker (BLNK) (AA 65-314) antibody
BLNK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (C-Term) antibody
Verified BLNK 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (AA 301-400) antibody
BLNK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D7 unconjugated

anti-B-Cell Linker (BLNK) (pTyr96) antibody
BLNK 适用: 人 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (AA 41-337) antibody
BLNK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (N-Term) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (pTyr96) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (pTyr84) antibody
BLNK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
抗原

B-Cell Linker (BLNK)

别名

BLNK

背景

Synonyms: bca, AGM4, BASH, LY57, SLP65, BLNK-S, SLP-65, B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, BLNK
Background: Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.

基因ID

29760

UniProt

Q8WV28

途径

BCR Signaling