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MFN2 抗体 (AA 1-120)

This anti-MFN2 antibody is a 兔 多克隆 antibody detecting MFN2 in WB, ELISA, IHC (p), FACS, IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 大鼠, 小鼠 和 兔. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN682528
发货至: 中国

Quick Overview for MFN2 抗体 (AA 1-120) (ABIN682528)

抗原

See all MFN2 抗体
MFN2 (Mitofusin 2 (MFN2))

适用

  • 65
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  • 2
  • 2
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人, 大鼠, 小鼠, 兔

宿主

  • 58
  • 23
  • 2

克隆类型

  • 56
  • 27
多克隆

标记

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  • 6
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  • 1
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This MFN2 antibody is un-conjugated

应用范围

  • 63
  • 48
  • 33
  • 17
  • 15
  • 13
  • 4
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  • 1
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 18
    • 7
    • 7
    • 5
    • 4
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    AA 1-120

    交叉反应

    人, 小鼠, 兔, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Mitofusin 2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Hui, Lu, Han, Zhou, Liu, Li, Jin: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).

    Ku, Ji, Zhang, Li, Sang: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).

  • 抗原

    MFN2 (Mitofusin 2 (MFN2))

    别名

    Mitofusin 2

    背景

    Synonyms: HSG, MARF, CMT2A, CPRP1, CMT2A2, Mitofusin-2, Transmembrane GTPase MFN2, MFN2, KIAA0214

    Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

    基因ID

    9927

    UniProt

    O95140

    途径

    Skeletal Muscle Fiber Development
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