OXSR1 抗体 (AA 201-300)
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北京 101111
Quick Overview for OXSR1 抗体 (AA 201-300) (ABIN681808)
抗原
See all OXSR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human OXSR1.
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亚型
- IgG
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anti-Oxidative-Stress Responsive 1 (OXSR1) (AA 1-527) antibody
OXSR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3A8 unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (AA 1-527) antibodyOXSR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A2-1A2 unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (AA 351-450) antibodyOXSR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C8 unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (AA 351-450) antibodyOXSR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6C7 unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (AA 351-450) antibodyOXSR1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 5E1 unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (AA 1-527) antibodyOXSR1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (pThr185) antibodyOXSR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) antibodyOXSR1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (AA 1-100) antibodyOXSR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxidative-Stress Responsive 1 (OXSR1) (pThr185) antibodyOXSR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))
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别名
- OXSR1
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背景
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Synonyms: KIAA1101, OSR 1, OSR1, Oxidative stress responsive 1, Oxidative stress responsive 1 protein, OXSR 1, Serine/threonine protein kinase OSR1.
Background: OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
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基因ID
- 9943
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途径
- Tube Formation
抗原
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