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PARD3 抗体 (AA 1201-1356) (FITC)

This FITC-conjugated 兔 多克隆 anti-PARD3 antibody specifically detects PARD3 in WB, IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN681725
发货至: 中国
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Quick Overview for PARD3 抗体 (AA 1201-1356) (FITC) (ABIN681725)

抗原

See all PARD3 抗体
PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PARD3 antibody is conjugated to FITC

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 1201-1356

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PARD-3

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

    别名

    PARD-3

    背景

    Synonyms: Baz, ASIP, PAR3, PARD-3, PARD3A, SE2-5T2, PPP1R118, SE2-5L16, SE2-5LT1, PAR3alpha, Partitioning defective 3 homolog, PAR-3, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3A

    Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.

    基因ID

    56288

    UniProt

    Q8TEW0

    途径

    Cell-Cell Junction Organization
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