RECK 抗体 (AA 801-900)
Quick Overview for RECK 抗体 (AA 801-900) (ABIN681418)
抗原
See all RECK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 801-900
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RECK
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Reversion-inducing-cysteine-rich Protein with Kazal Motif Is Involved in Intimal Hyperplasia in Carotid Arteries: A New Insight in the Prevention of Restenosis after Vascular Angioplasty." in: Annals of vascular surgery, Vol. 29, Issue 6, pp. 1293-9, (2015) (PubMed).
: "Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECK." in: Journal of cellular physiology, Vol. 229, Issue 7, pp. 845-55, (2014) (PubMed).
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: "Reversion-inducing-cysteine-rich Protein with Kazal Motif Is Involved in Intimal Hyperplasia in Carotid Arteries: A New Insight in the Prevention of Restenosis after Vascular Angioplasty." in: Annals of vascular surgery, Vol. 29, Issue 6, pp. 1293-9, (2015) (PubMed).
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- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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别名
- RECK
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背景
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Synonyms: ST15, Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK
Background: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
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基因ID
- 8434
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UniProt
- O95980
抗原
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