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HDAC7 抗体 (Cy7)

This anti-HDAC7 antibody is a 兔 多克隆 antibody detecting HDAC7 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN681259
发货至: 中国

Quick Overview for HDAC7 抗体 (Cy7) (ABIN681259)

抗原

See all HDAC7 抗体
HDAC7 (Histone Deacetylase 7 (HDAC7))

适用

  • 99
  • 66
  • 54
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 108
  • 6

克隆类型

  • 100
  • 14
多克隆

标记

  • 54
  • 8
  • 8
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This HDAC7 antibody is conjugated to Cy7

应用范围

  • 75
  • 45
  • 21
  • 15
  • 14
  • 14
  • 8
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HDAC7

    亚型

    IgG
  • 应用备注

    IF(IHC-P)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HDAC7 (Histone Deacetylase 7 (HDAC7))

    别名

    HDAC7

    背景

    Synonyms: HD 7a, HD7a, HDAC 7, HDAC 7A, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, DKFZP586J0917, OTTHUMP00000202813, OTTHUMP00000202814, FLJ99588, HDAC7_HUMAN.

    Background: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

    途径

    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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