GAB2 抗体 (AA 601-676)
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北京 101111
Quick Overview for GAB2 抗体 (AA 601-676) (ABIN681178)
抗原
See all GAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 601-676
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Gab2
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亚型
- IgG
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anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr452) antibody
GAB2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer159) antibodyGAB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 273-484) antibodyGAB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (Ser159) antibodyGAB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 3-30), (N-Term) antibodyGAB2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21209 unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 357-607) antibodyGAB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer623) antibodyGAB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr643) antibodyGAB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (C-Term) antibodyGAB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (Ser623) antibodyGAB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "K48-Linked Ubiquitination Contributes to Nicotine-Augmented Bone Marrow-Derived Dendritic-Cell-Mediated Adaptive Immunity." in: Vaccines, Vol. 9, Issue 3, (2021) (PubMed).
: "PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-κB Inactivation." in: Journal of immunology research, Vol. 2018, pp. 5070573, (2018) (PubMed).
: "Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model." in: Synapse (New York, N.Y.), Vol. 68, Issue 4, pp. 168-77, (2014) (PubMed).
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: "K48-Linked Ubiquitination Contributes to Nicotine-Augmented Bone Marrow-Derived Dendritic-Cell-Mediated Adaptive Immunity." in: Vaccines, Vol. 9, Issue 3, (2021) (PubMed).
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- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
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别名
- Gab2
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背景
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Synonyms: GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, pp1, GAB2, KIAA571
Background: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
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基因ID
- 9846
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UniProt
- Q9UQC2
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
抗原
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