CRHR2 抗体 (AA 51-150)
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北京 101111
Quick Overview for CRHR2 抗体 (AA 51-150) (ABIN680773)
抗原
See all CRHR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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特异性
- This antibody may cross react with CRHR1.
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CRHR2
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
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别名
- CRHR2
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背景
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Synonyms: CRF2, CRFR2, CRF-RB, HM-CRF, Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R
Background: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
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基因ID
- 1395
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UniProt
- Q13324
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour
抗原
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