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ARHGAP17 抗体 (AA 451-550)

This anti-ARHGAP17 antibody is a 兔 多克隆 antibody detecting ARHGAP17 in ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN679343
发货至: 中国

Quick Overview for ARHGAP17 抗体 (AA 451-550) (ABIN679343)

抗原

See all ARHGAP17 抗体
ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

适用

  • 30
  • 12
  • 12
  • 2
大鼠

宿主

  • 31

克隆类型

  • 30
多克隆

标记

  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This ARHGAP17 antibody is un-conjugated

应用范围

  • 24
  • 14
  • 10
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 451-550

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Drosophila

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from fruit fly ARHGAP17/Nadrin

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

    别名

    ARHGAP17

    背景

    Synonyms: ARHGAP17, NADRIN, Neuron associated developmentally regulated protein, Rho GTPase activating protein 17, RhoGAP interacting with CIP4 homologs protein 1, RICH 1, RICH1, WBP15, MST066, MST110, MSTP038, PP367, PP4534, Rho type GTPase activating protein 17, RhoGAP interacting with CIP4 homologs 1, RICH1B.

    Background: ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

    基因ID

    55114
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