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Prosaposin 抗体 (AA 421-524)

This anti-Prosaposin antibody is a 兔 多克隆 antibody detecting Prosaposin in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN678923
发货至: 中国

Quick Overview for Prosaposin 抗体 (AA 421-524) (ABIN678923)

抗原

See all Prosaposin (PSAP) 抗体
Prosaposin (PSAP)

适用

  • 51
  • 23
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宿主

  • 45
  • 21

克隆类型

  • 46
  • 20
多克隆

标记

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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Prosaposin antibody is un-conjugated

应用范围

  • 53
  • 28
  • 23
  • 14
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  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 421-524

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PSAP

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Prosaposin (PSAP)

    别名

    PSAP

    背景

    Synonyms: A1 activator, Cerebroside sulfate activator, Co-beta-glucosidase, Component C, CSAct, Dispersin, GLBA, Glucosylceramidase activator, Proactivator polypeptide, Proactivator polypeptide precursor, Prosaposin sphingolipid activator protein 1, prosaposin variant Gaucher disease and variant metachromatic leukodystrophy, Protein A, Protein C, PSAP, SAP-1, SAP-2, SAP_HUMAN, SAP1, Saposin A, Saposin B, Saposin B Val, Saposin C, Saposin-D, Saposins, Sphingolipid activator protein 1, Sphingolipid activator protein 2, Sulfated glycoprotein 1, Sulfatide/GM1 activator.

    Background: PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D, which are similar to each other and are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.

    基因ID

    5660

    UniProt

    P07602

    途径

    Positive Regulation of Endopeptidase Activity
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