MTDH 抗体 (AA 131-230) (HRP)
Quick Overview for MTDH 抗体 (AA 131-230) (HRP) (ABIN678872)
抗原
See all MTDH 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 131-230
-
交叉反应
- 人
-
预测反应
- Mouse,Rat,Dog,Cow,Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human AEG-1
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- MTDH (Metadherin (MTDH))
-
别名
- LYRIC
-
背景
-
Synonyms: 3D3, AEG1, AEG-1, LYRIC, LYRIC/3D3, Protein LYRIC, 3D3/LYRIC, Astrocyte elevated gene-1 protein, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein, MTDH
Background: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
-
基因ID
- 92140
-
UniProt
- Q86UE4
-
途径
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
抗原
-