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IL-33 抗体 (AA 1-111)

This anti-IL-33 antibody is a 兔 多克隆 antibody detecting IL-33 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN678638
发货至: 中国

Quick Overview for IL-33 抗体 (AA 1-111) (ABIN678638)

抗原

See all IL-33 (IL33) 抗体
IL-33 (IL33) (Interleukin 33 (IL33))

适用

  • 80
  • 48
  • 43
  • 10
  • 1
人, 小鼠

宿主

  • 107
  • 38
  • 4
  • 2
  • 2
  • 1
  • 1

克隆类型

  • 113
  • 42
多克隆

标记

  • 92
  • 23
  • 13
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-33 antibody is un-conjugated

应用范围

  • 109
  • 64
  • 62
  • 45
  • 29
  • 27
  • 14
  • 13
  • 13
  • 11
  • 9
  • 5
  • 5
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  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 18
    • 16
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-111

    交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IL-33

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Saied, El-Etreby: "The role and prognostic value of inducible nitric oxide synthase (iNOS) and interleukin-33 (IL-33) in serous and mucinous epithelial ovarian tumours." in: Annals of diagnostic pathology, Vol. 27, pp. 62-68, (2017) (PubMed).

  • 抗原

    IL-33 (IL33) (Interleukin 33 (IL33))

    别名

    IL-33

    背景

    Synonyms: Interleukin-33/Nuclear factor from high endothelial venules, IL33, C9orf26, CHROMOSOME 9 OPEN READING FRAME 26, DKFZp586H0523, DVS27, DVS27 related protein, IL 1F11, IL 33, IL1F11, Interleukin 1 family member 11, Interleukin 33, INTERLEUKIN 33 NFHEV, Interleukin 33 precursor, Interleukin33, NF HEV, NFEHEV, NFHEV, Nuclear factor from high endothelial venules, RP11 575C20.2 IL33_HUMAN.

    Background: IL33 is a cytokine which belongs to the IL-1 superfamily, and it induces helper T cells to produce type 2 cytokines. This cytokine was previously named NF-HEV 'nuclear factor (NF) in high endothelial venules' (HEVs), as it was originally identified in these specialized cells.IL33 mediates its biological effects by interacting with the receptors ST2 and IL-1 Receptor Accessory Protein, activating intracellular molecules in the NF-kappaB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-4, IL-5 and IL-13) from polarized Th2 cells. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the the severe pathological changes observed in mucosal organs following administration of IL33.

    基因ID

    90865

    UniProt

    O95760

    途径

    Production of Molecular Mediator of Immune Response
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