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OLR1 抗体 (AA 201-273)

Name: OLR1 抗体 (AA 201-273)
SKU: ABIN676988
Availability: OutOfStock

Cited in 6+ publications. This anti-OLR1 antibody is a 兔多克隆 antibody detecting OLR1 in WB, ELISA, ICC, FACS, IF (p), IF (cc), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠和兔.

This image was generously provided by Zu Yue Deng from Zhejiang University of Technology. (OLR1 抗体 (AA 201-273))

Formalin-fixed and paraffin embedded rat aorta labeled with Anti-LOX-1 Polyclonal Antibody, Unconjugated (ABIN676988) followed by conjugation to the secondary antibody and DAB staining (OLR1 抗体 (AA 201-273))

IHC

Human A549 cells probed with Rabbit Anti-LOX1 Polyclonal Antibody, Unconjugated . (OLR1 抗体 (AA 201-273))

FACS

Formalin-fixed and paraffin embedded rat aorta labeled with Anti-LOX-1 Polyclonal Antibody, Unconjugated followed by conjugation to the secondary antibody and DAB staining (OLR1 抗体 (AA 201-273))

IHC (p)

RSC96 cells probed with LOX 1 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (OLR1 抗体 (AA 201-273))

FACS

5 images

(6 references)

产品编号 ABIN676988

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for OLR1 抗体 (AA 201-273) (ABIN676988)

抗原

See all OLR1 抗体

OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

适用

人, 小鼠, 大鼠, 兔

宿主

兔

克隆类型

多克隆

标记

This OLR1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

抗原表位
15

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2

1

1

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1

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1

1

1

1

1

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AA 201-273

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from Rabbit LOX-1

亚型

IgG
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 51-314) antibody
OLR1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 57-270) antibody
OLR1 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 64-92) antibody
OLR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21925 unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 58-273) antibody
OLR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 60-312) antibody
OLR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 81-273) antibody
OLR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (N-Term) antibody
OLR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) antibody (APC)
OLR1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15C4 APC

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 1-273) antibody
OLR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) antibody
OLR1 适用: 人 ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 15C4 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Shibata, Shibata, Maemura, Kondo, Harada-Shiba: "Pathological and molecular analyses of atherosclerotic lesions in ApoE-knockout mice." in: Medical molecular morphology, (2017) (PubMed).

Gao, Zhao, Li, Lin, Jiang, Wang, Hu, Xu, Peng, He, Zhu: "LOX-1 and TLR4 affect each other and regulate the generation of ROS in A. fumigatus keratitis." in: International immunopharmacology, Vol. 40, pp. 392-399, (2016) (PubMed).

Deng, Hu, Xin, Gang: "Resveratrol alleviates vascular inflammatory injury by inhibiting inflammasome activation in rats with hypercholesterolemia and vitamin D2 treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 64, Issue 5, pp. 321-32, (2015) (PubMed).

Li, Zhao, Che, Lin, Li, Hu, Jiang, Liu: "The Role of LOX-1 in Innate Immunity to Aspergillus fumigatus in Corneal Epithelial Cells." in: Investigative ophthalmology & visual science, Vol. 56, Issue 6, pp. 3593-603, (2015) (PubMed).

Wu, Tang, Jiang, Li, Jiang, Liu: "PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway." in: Molecular and cellular biochemistry, Vol. 359, Issue 1-2, pp. 347-58, (2011) (PubMed).

Jeng, Dyson: "Direct measurement of the aspartic acid 26 pKa for reduced Escherichia coli thioredoxin by 13C NMR." in: Biochemistry, Vol. 35, Issue 1, pp. 1-6, (1996) (PubMed).
抗原

OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

别名

LOX 1

背景

Synonyms: LOX1, LOX-1, Oxidized low-density lipoprotein receptor 1, Ox-LDL receptor 1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, OLR1
Background: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).

基因ID

100009322

UniProt

Q9XTA8