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OLR1 抗体 (AA 201-273)

Name: OLR1 抗体 (AA 201-273)
SKU: ABIN676988
Availability: OutOfStock

This anti-OLR1 antibody (ABIN676988) is a Rabbit Polyclonal antibody detecting OLR1 in WB, ELISA, ICC, IF (p), FACS, IF (cc), IHC (p), IHC (fro). Suitable for Human, Mouse, Rat, Rabbit.

This image was generously provided by Zu Yue Deng from Zhejiang University of Technology. (OLR1 抗体 (AA 201-273))

Formalin-fixed and paraffin embedded rat aorta labeled with Anti-LOX-1 Polyclonal Antibody, Unconjugated (ABIN676988) followed by conjugation to the secondary antibody and DAB staining (OLR1 抗体 (AA 201-273))

IHC

Human A549 cells probed with Rabbit Anti-LOX1 Polyclonal Antibody, Unconjugated . (OLR1 抗体 (AA 201-273))

FACS

Formalin-fixed and paraffin embedded rat aorta labeled with Anti-LOX-1 Polyclonal Antibody, Unconjugated followed by conjugation to the secondary antibody and DAB staining (OLR1 抗体 (AA 201-273))

IHC (p)

RSC96 cells probed with LOX 1 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (OLR1 抗体 (AA 201-273))

FACS

5 images

(6 references)

产品编号 ABIN676988

发货至: 中国

Datasheet as PDF

Quick Overview for OLR1 抗体 (AA 201-273) (ABIN676988)

抗原

See all OLR1 抗体

OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

适用

人, 小鼠, 大鼠, 兔

宿主

兔

克隆类型

多克隆

标记

This OLR1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

抗原表位
15

7

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4

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2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 201-273

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from Rabbit LOX-1

亚型

IgG
anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 51-314) antibody
OLR1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 57-270) antibody
OLR1 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 64-92) antibody
OLR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21925 unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 58-273) antibody
OLR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 60-312) antibody
OLR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 81-273) antibody
OLR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (N-Term) antibody
OLR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) antibody (APC)
OLR1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15C4 APC

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 1-273) antibody
OLR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) antibody
OLR1 适用: 人 ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 15C4 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Shibata, Shibata, Maemura, Kondo, Harada-Shiba: "Pathological and molecular analyses of atherosclerotic lesions in ApoE-knockout mice." in: Medical molecular morphology, (2017) (PubMed).

Gao, Zhao, Li, Lin, Jiang, Wang, Hu, Xu, Peng, He, Zhu: "LOX-1 and TLR4 affect each other and regulate the generation of ROS in A. fumigatus keratitis." in: International immunopharmacology, Vol. 40, pp. 392-399, (2016) (PubMed).

Deng, Hu, Xin, Gang: "Resveratrol alleviates vascular inflammatory injury by inhibiting inflammasome activation in rats with hypercholesterolemia and vitamin D2 treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 64, Issue 5, pp. 321-32, (2015) (PubMed).

Li, Zhao, Che, Lin, Li, Hu, Jiang, Liu: "The Role of LOX-1 in Innate Immunity to Aspergillus fumigatus in Corneal Epithelial Cells." in: Investigative ophthalmology & visual science, Vol. 56, Issue 6, pp. 3593-603, (2015) (PubMed).

Wu, Tang, Jiang, Li, Jiang, Liu: "PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway." in: Molecular and cellular biochemistry, Vol. 359, Issue 1-2, pp. 347-58, (2011) (PubMed).

Jeng, Dyson: "Direct measurement of the aspartic acid 26 pKa for reduced Escherichia coli thioredoxin by 13C NMR." in: Biochemistry, Vol. 35, Issue 1, pp. 1-6, (1996) (PubMed).
抗原

OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

别名

LOX 1

背景

Synonyms: LOX1, LOX-1, Oxidized low-density lipoprotein receptor 1, Ox-LDL receptor 1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, OLR1
Background: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).

基因ID

100009322

UniProt

Q9XTA8