PAFAH1B1 抗体 (AA 311-410)
Quick Overview for PAFAH1B1 抗体 (AA 311-410) (ABIN676868)
抗原
See all PAFAH1B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-410
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LIS1
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亚型
- IgG
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anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (C-Term) antibody
Verified PAFAH1B1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 1-110) antibodyPAFAH1B1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A5 unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) antibodyPAFAH1B1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (N-Term) antibodyPAFAH1B1 适用: 人, 大鼠, 小鼠, Cow, 犬, 斑马鱼, 马, 兔, Pig, 豚鼠, 小鸡, 非洲爪蟾, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) antibodyPAFAH1B1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 76-110), (N-Term) antibodyPAFAH1B1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50845 unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 40-155) antibodyPAFAH1B1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 1-110) antibodyPAFAH1B1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (C-Term) antibodyPAFAH1B1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 71-120) antibodyPAFAH1B1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, Pig, 豚鼠, 小鸡, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
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别名
- LIS1
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背景
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Synonyms: MDS, LIS1, LIS2, MDCR, PAFAH, Platelet-activating factor acetylhydrolase IB subunit alpha, Lissencephaly-1 protein, LIS-1, PAF acetylhydrolase 45 kDa subunit, PAF-AH 45 kDa subunit, PAF-AH alpha, PAFAH alpha, PAFAH1B1, PAFAHA
Background: Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity). Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.
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基因ID
- 5048
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UniProt
- P43034
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途径
- M Phase, Regulation of Cell Size
抗原
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