ITGAV/ITGB1 抗体 (Cy5)
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北京 101111
Quick Overview for ITGAV/ITGB1 抗体 (Cy5) (ABIN676722)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
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亚型
- IgG
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anti-Integrin alpha V, Integrin beta 1 (ITGAV/ITGB1) antibody
ITGAV/ITGB1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ITGAV/ITGB1 (Integrin alpha V, Integrin beta 1 (ITGAV/ITGB1))
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Sub Type
- Cocktail
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背景
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Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29
Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).
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基因ID
- 3685, 3688
抗原
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