MITF 抗体 (AA 351-450)
Quick Overview for MITF 抗体 (AA 351-450) (ABIN676373)
抗原
See all MITF 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 351-450
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                                            交叉反应
- 小鼠
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                                            预测反应
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from human MITF
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                                            亚型
- IgG
 
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                                            应用备注
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                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IF(IHC-P) 1:50-200
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
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                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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                                            有效期
- 12 months
 
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    - 
                                            : "Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta."    in: Scientific reports, Vol. 7, Issue 1, pp. 12063, (2019)         (PubMed).        
 : "Novel Transgenic Mouse Model of Polycystic Kidney Disease." in: The American journal of pathology, Vol. 187, Issue 9, pp. 1916-1922, (2017) (PubMed).
 : "Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells." in: Journal of food science, Vol. 81, Issue 8, pp. H2085-92, (2016) (PubMed).
 
 
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                                            : "Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta."    in: Scientific reports, Vol. 7, Issue 1, pp. 12063, (2019)         (PubMed).        
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    - MITF (Microphthalmia-Associated Transcription Factor (MITF))
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                                            别名
- Mitf
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                                            背景
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                        Synonyms: MI, WS2, CMM8, WS2A, bHLHe32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, MITF Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. 
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                                            基因ID
- 4286
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                                            UniProt
- O75030
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                                            途径
- Chromatin Binding
 抗原
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