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MITF 抗体 (AA 351-450)

There are 4+ publications for this product available. The 兔 多克隆 anti-MITF antibody is suitable to detect MITF in samples from 小鼠. It has been validated for WB, ELISA, IHC (p) 和 IF (p).
产品编号 ABIN676373
发货至: 中国
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Quick Overview for MITF 抗体 (AA 351-450) (ABIN676373)

抗原

See all MITF 抗体
MITF (Microphthalmia-Associated Transcription Factor (MITF))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This MITF antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    AA 351-450

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MITF

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Rice, Cebra-Thomas, Haugas, Partanen, Rice, Gilbert: "Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta." in: Scientific reports, Vol. 7, Issue 1, pp. 12063, (2019) (PubMed).

    Kito, Saigo, Takeuchi: "Novel Transgenic Mouse Model of Polycystic Kidney Disease." in: The American journal of pathology, Vol. 187, Issue 9, pp. 1916-1922, (2017) (PubMed).

    Han, Sung, Lee: "Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells." in: Journal of food science, Vol. 81, Issue 8, pp. H2085-92, (2016) (PubMed).

  • 抗原

    MITF (Microphthalmia-Associated Transcription Factor (MITF))

    别名

    Mitf

    背景

    Synonyms: MI, WS2, CMM8, WS2A, bHLHe32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, MITF

    Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

    基因ID

    4286

    UniProt

    O75030

    途径

    Chromatin Binding
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