CCR7 抗体 (AA 25-59) (PE)
Quick Overview for CCR7 抗体 (AA 25-59) (PE) (ABIN674734)
抗原
See all CCR7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-59
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交叉反应
- 人, 小鼠, 大鼠, 绵羊
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预测反应
- Dog
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse CCR7
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亚型
- IgG
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应用备注
- FCM 1:20-100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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别名
- CCR7/CD197
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背景
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Synonyms: EBI1, CCR-7, CD197, Ebi1h, Cdw197, Cmkbr7, CC-CKR-7, C-C chemokine receptor type 7, C-C CKR-7, Epstein-Barr virus-induced G-protein coupled receptor 1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, Ccr7
Background: CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.
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基因ID
- 12775
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UniProt
- P47774
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途径
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
抗原
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