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PAR1 抗体 (AA 267-316)

This anti-PAR1 antibody is a 兔 多克隆 antibody detecting PAR1 in WB. Suitable for 人, 大鼠, 小鼠, Pig 和 兔. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN6746560
发货至: 中国

Quick Overview for PAR1 抗体 (AA 267-316) (ABIN6746560)

抗原

See all PAR1 (F2R) 抗体
PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

适用

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  • 2
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人, 大鼠, 小鼠, Pig, 兔

宿主

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克隆类型

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多克隆

标记

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This PAR1 antibody is un-conjugated

应用范围

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  • 9
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Western Blotting (WB)
  • 抗原表位

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    AA 267-316

    特异性

    Human F2R / Thrombin Receptor

    预测反应

    Percent identity by BLAST analysis: Mouse, Rat (100%) Dog (92%) Pig (85%) Rabbit (84%).

    纯化方法

    Immunoaffinity purified

    免疫原

    Synthetic peptide located between aa267-316 of human F2R (P25116, NP_001983). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Mouse, Rat (100%), Gibbon, Baboon, Monkey, Galago, Marmoset, Hamster, Dog, Horse (92%), Pig (85%), Rabbit (84%).

    Type of Immunogen: Synthetic peptide
  • 应用备注

    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS with 2 % sucrose

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Gradin, Larsson, Marklund, Gullberg: "Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells." in: The Journal of cell biology, Vol. 140, Issue 1, pp. 131-41, (1998) (PubMed).

    Horwitz, Shen, He, Dittmar, Neef, Chen, Schubart: "The microtubule-destabilizing activity of metablastin (p19) is controlled by phosphorylation." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8129-32, (1997) (PubMed).

    Larsson, Marklund, Gradin, Brattsand, Gullberg: "Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis." in: Molecular and cellular biology, Vol. 17, Issue 9, pp. 5530-9, (1997) (PubMed).

  • 抗原

    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

    别名

    F2R / Thrombin Receptor / PAR1

    背景

    Name/Gene ID: F2R
    Subfamily: Proteinase-activated
    Family: GPCR

    Synonyms: F2R, CF2R, Coagulation factor II receptor, PAR1, PAR-1, Thrombin receptor, TR, HTR, Protease-activated receptor 1

    基因ID

    2149

    NCBI登录号

    NP_001983

    UniProt

    P25116

    途径

    Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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