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PDE8A 抗体 (AA 681-730)

Cited in 4+ publications. This 兔 多克隆 anti-PDE8A antibody specifically detects PDE8A in WB. The antibody is reactive with 人, 小鼠, 大鼠, 猴, 兔, Cow 和 Pig samples.
产品编号 ABIN6746532
发货至: 中国
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Quick Overview for PDE8A 抗体 (AA 681-730) (ABIN6746532)

抗原

See all PDE8A 抗体
PDE8A (phosphodiesterase 8A (PDE8A))

适用

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人, 小鼠, 大鼠, 猴, 兔, Cow, Pig

宿主

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克隆类型

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多克隆

标记

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This PDE8A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 681-730

    特异性

    Human PDE8A

    预测反应

    Percent identity by BLAST analysis: Human, Mouse, Rat, Bovine, Rabbit (100%) Dog, Horse, Guinea pig, Zebrafish (92%) Chicken (85%).

    纯化方法

    Immunoaffinity purified

    免疫原

    Synthetic peptide located between aa681-730 of human PDE8A (O60658, NP_775656). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Elephant, Bovine, Rabbit, Pig (100%), Dog, Horse, Guinea pig, Zebrafish (92%), Xenopus, Drosophila (91%), Marmoset, Bat, Opossum, Turkey, Zebra finch, Chicken, Lizard, Stickleback (85%).

    Type of Immunogen: Synthetic peptide
  • 应用备注

    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS with 2 % sucrose

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Shahan, Sorenson, Simpson, Kefalides, Lewis: "Tyrosine kinase activation in response to fungal spores is primarily dependent on endogenous reactive oxygen production in macrophages." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10175-81, (2000) (PubMed).

    Yang, Malek, Desiderio: "An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo." in: The Journal of biological chemistry, Vol. 270, Issue 35, pp. 20832-40, (1995) (PubMed).

    Aoki, Isselbacher, Pillai: "Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 22, pp. 10606-9, (1994) (PubMed).

    Vetrie, Vorechovský, Sideras, Holland, Davies, Flinter, Hammarström, Kinnon, Levinsky, Bobrow: "The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases." in: Nature, Vol. 361, Issue 6409, pp. 226-33, (1993) (PubMed).

  • 抗原

    PDE8A (phosphodiesterase 8A (PDE8A))

    别名

    PDE8A

    背景

    Name/Gene ID: PDE8A
    Subfamily: PDE - cAMP-specific, high affinity
    Family: Phosphodiesterase

    Synonyms: PDE8A, Phosphodiesterase 8A, HsT19550

    基因ID

    5151

    NCBI登录号

    NP_775656

    UniProt

    O60658

    途径

    cAMP Metabolic Process
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