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CYR61 抗体 (AA 251-379) (Biotin)

This anti-CYR61 antibody is a 兔 多克隆 antibody detecting CYR61 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN674501
发货至: 中国
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Beijing Economic Technological Development Area
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Quick Overview for CYR61 抗体 (AA 251-379) (Biotin) (ABIN674501)

抗原

See all CYR61 抗体
CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

适用

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宿主

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克隆类型

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多克隆

标记

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This CYR61 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 251-379

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Cyr61

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

    别名

    Cyr61

    背景

    Synonyms: CCN1, GIG1, IGFBP10, Protein CYR61, CCN family member 1, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1, CYR61

    Background: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

    基因ID

    3491

    UniProt

    O00622

    途径

    Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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