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Doublecortin 抗体 (Cy3)

This anti-Doublecortin antibody is a 兔 多克隆 antibody detecting Doublecortin in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN674187
发货至: 中国

Quick Overview for Doublecortin 抗体 (Cy3) (ABIN674187)

抗原

See all Doublecortin (DCX) 抗体
Doublecortin (DCX)

适用

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人, 小鼠, 大鼠

宿主

  • 94
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克隆类型

  • 91
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多克隆

标记

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This Doublecortin antibody is conjugated to Cy3

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Doublecortin

    亚型

    IgG
  • 应用备注

    IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Doublecortin (DCX)

    别名

    Doublecortin

    背景

    Synonyms: Doublecortex, DBCN, Dbct, DC, Doublin, Lis X, Lissencephalin X, Lissencephaly X linked, Lissencephaly X linked doublecortin, LISX, Neuronal migration protein doublecortin, SCLH, XLIS.

    Background: Neuronal Marker Doublecortin (DCX) is a microtubule-associated protein expressed almost exclusively in immature neurons. Neuronal precursors begin to express DCX shortly after exiting the cell cycle, and continue to express DCX for 2-3 weeks as the cells mature into neurons. Downregulation of DCX begins after 2 weeks, and occurs at the same time that these cells begin to express, a marker for mature neurons. Due to the nearly exclusive expression of DCX in developing neurons, this protein has been used increasingly as a marker for neurogenesis. Indeed, the levels of DCX expression increase in response to exercise, which occurs in parallel with increased BrdU labelling, currently a "gold standard" in measuring neurogenesis.

    基因ID

    1641
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