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Aggrecan 抗体 (AA 101-220)

This anti-Aggrecan antibody is a 兔 多克隆 antibody detecting Aggrecan in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 大鼠, 小鼠 和 兔. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN673599
发货至: 中国

Quick Overview for Aggrecan 抗体 (AA 101-220) (ABIN673599)

抗原

See all Aggrecan (ACAN) 抗体
Aggrecan (ACAN)

适用

  • 89
  • 47
  • 33
  • 18
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠, 兔

宿主

  • 90
  • 25
  • 1
  • 1

克隆类型

  • 83
  • 34
多克隆

标记

  • 64
  • 15
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aggrecan antibody is un-conjugated

应用范围

  • 86
  • 56
  • 38
  • 30
  • 22
  • 13
  • 13
  • 12
  • 8
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 10
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-220

    交叉反应

    人, 小鼠, 兔, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Aggrecan core protein

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Hu, Yang, Chen, Sun, Lin, Yang: "Optimization of puncture injury to rat caudal disc for mimicking early degeneration of intervertebral disc." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2017) (PubMed).

    Zhao, Hao, Wang, Wang: "Effect of Choline on the Composition and Degradation Enzyme of Extracellular Matrix of Mice Chondrocytes Exposed to Fluoride." in: Biological trace element research, (2016) (PubMed).

    Liu, Yu, Ma, Xiang, Hu, Chen: "Lentivirus-mediated TGF-β3, CTGF and TIMP1 gene transduction as a gene therapy for intervertebral disc degeneration in an in vivo rabbit model." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1399-1404, (2016) (PubMed).

    Shi, Ma, Zhang, Li, Jiang, Qin: "Hypoxia combined with spheroid culture improves cartilage specific function in chondrocytes." in: Integrative biology : quantitative biosciences from nano to macro, (2015) (PubMed).

    Lei, Li, Li, Gao, Chen, Jin: "Mesenchymal stem cell characteristics of dental pulp and periodontal ligament stem cells after in vivo transplantation." in: Biomaterials, Vol. 35, Issue 24, pp. 6332-43, (2014) (PubMed).

    Ren, Liu, Ma, Liu, Diao, Yang, Zhang, Xi, Hu: "Treatment of rabbit intervertebral disc degeneration with co-transfection by adeno-associated virus-mediated SOX9 and osteogenic protein-1 double genes in vivo." in: International journal of molecular medicine, Vol. 32, Issue 5, pp. 1063-8, (2014) (PubMed).

  • 抗原

    Aggrecan (ACAN)

    别名

    Aggrecan core protein 1

    背景

    Synonyms: AGC1, SEDK, AGCAN, CSPG1, MSK16, CSPGCP, Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, ACAN

    Background: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

    基因ID

    176

    UniProt

    P16112

    途径

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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