HCN1 抗体 (AA 346-368)
Quick Overview for HCN1 抗体 (AA 346-368) (ABIN6735304)
抗原
See all HCN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 346-368
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特异性
- The pore region of HCN1 (HCNP15-P) is very conserved among various HCNs. HCN1: mouse, rat, human, rabbit=100 % , HCN2: mouse, rat, human (86 %), HCN3: mouse (95 %), rat (90 %), HCN4: rat, human (95 %). The HCNP15-P sequence is also conserved in insect (Helothis virescens, 78 %), Drosophila (78 %) and Sea urchin (S. purpuratus, 69 %) HCNs. Therefore, antibodies to HCNP15-P should react with most HCNs and related sequences. Antibody reactivity in various species is not known. The HCNP15-P control peptide, because of its low MW (<3kD), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 μg control peptide per 1 μg of aff pure IgG or 1 μL antiserum) to confirm antibody specificity. This antibody may be useful in studying various HCNs and to examine the possibility of immunoblocking the pore region and impact on the functionality of HCNs proteins.
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纯化方法
- Immunoaffinity purified
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免疫原
- A 23-aa peptide sequence corresponding to the pore region of human HCN1 corresponding to amino acids 346-368.
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亚型
- IgG
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anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody
HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 unconjugated
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (HRP)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 HRP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (FITC)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 FITC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Biotin)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Biotin
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (PE)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 PE
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (PerCP)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 PerCP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (APC)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 APC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 488)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 488
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 594)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 594
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 390)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 390
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应用备注
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Approved: ELISA (1:10000 - 1:100000), WB (1 - 10 μg/mL)
Usage: Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000 for neat serum and 1-10 μg/mL for affinity pure using ECL. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 % BSA.
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注意事项
- avoid freeze thaw cycles. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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- HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))
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别名
- HCN1
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背景
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Name/Gene ID: HCN1
Subfamily: Potassium channel - cyclic nucleotide gated
Family: Ion Channel
Synonyms: HCN1, BCNG1, BCNG-1, HAC2, HAC-2 -
基因ID
- 348980
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UniProt
- O60741
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途径
- Asymmetric Protein Localization
抗原
-
