CD3 抗体 (iFluor™700)
Quick Overview for CD3 抗体 (iFluor™700) (ABIN6731068)
抗原
See all CD3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD3 iFluor™ 700 Antibody
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产品特性
- CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human peripheral blood lymphocytes
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD3
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别名
- CD3
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基因ID
- 916
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NCBI登录号
- NM_000733
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UniProt
- P07766
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途径
- TCR Signaling, Ubiquitin Proteasome Pathway
抗原
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