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Fc epsilon RI/FCER1A 抗体 (FITC)

The Armenian Hamster 单克隆 anti-Fc epsilon RI/FCER1A antibody is suitable to detect Fc epsilon RI/FCER1A in samples from 小鼠. It has been validated for FACS.
产品编号 ABIN6728424
发货至: 中国
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Quick Overview for Fc epsilon RI/FCER1A 抗体 (FITC) (ABIN6728424)

抗原

See all Fc epsilon RI/FCER1A (FCER1A) 抗体
Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

适用

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小鼠

宿主

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Armenian Hamster

克隆类型

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单克隆

标记

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This Fc epsilon RI/FCER1A antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

MAR-1
  • 亚型

    IgG
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: FITC Armenian Hamster IgG Isotype Control (ABIN7469875)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

    别名

    FcepsilonRIalpha

    背景

    High affinity immunoglobulin epsilon receptor subunit alpha,Fc-epsilon RI-alpha,FcERI,Fcer1a,FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

    基因ID

    14125

    UniProt

    P20489

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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