KISS1 抗体 (AA 81-145) (Biotin)
Quick Overview for KISS1 抗体 (AA 81-145) (Biotin) (ABIN672728)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-145
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特异性
- This antibody detects Kisspeptin-10 region of Kisspeptin.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Sheep
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KISS1
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亚型
- IgG
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anti-Kisspeptin (KISS1) (AA 46-146) antibody
KISS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Kisspeptin (KISS1) (AA 81-145) antibodyKISS1 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- KISS1 (Kisspeptin (KISS1))
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别名
- Kisspeptin
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背景
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Synonyms: HH13, KiSS-1, Metastasis-suppressor KiSS-1, Kisspeptin-1, KISS1, PP598
Background: Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-1 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-1, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-1 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
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基因ID
- 3814
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UniProt
- Q15726
抗原
-
