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CD22 抗体 (Alexa Fluor 488)

This anti-CD22 antibody is a 小鼠 单克隆 antibody detecting CD22 in FACS. Suitable for 人.
产品编号 ABIN6722324
发货至: 中国

Quick Overview for CD22 抗体 (Alexa Fluor 488) (ABIN6722324)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD22 antibody is conjugated to Alexa Fluor 488

应用范围

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Flow Cytometry (FACS)

克隆位点

BU59
  • 亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    背景

    Synonyms: B-cell receptor CD22,Cd22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,Lyb-8, Siglec2

    Background: CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

    基因ID

    933

    UniProt

    P20273
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