KCNMA1 抗体 (AA 1131-1236)
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北京 101111
Quick Overview for KCNMA1 抗体 (AA 1131-1236) (ABIN672426)
抗原
See all KCNMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1131-1236
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BK channel
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亚型
- IgG
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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (C-Term) antibody
KCNMA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 兔, 犬, 马, 豚鼠, 绵羊 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1-86) antibodyKCNMA1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 124-467) antibodyKCNMA1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 199-213), (Extracellular) antibodyKCNMA1 适用: 大鼠 IHC, WB, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1080-1129) antibodyKCNMA1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 绵羊, 小鸡, 非洲爪蟾, 猴, Pig, Bat IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (Internal Region) antibodyKCNMA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 兔, 犬, 小鸡, 非洲爪蟾, 猴, Pig, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1184-1200), (Intracellular) antibodyKO Validated KCNMA1 适用: 小鼠 IHC, WB, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1097-1196), (Intracellular) antibodyKCNMA1 适用: 小鼠 WB 宿主: 豚鼠 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (Internal Region) antibodyKCNMA1 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 118-152) antibodyKCNMA1 适用: 人 WB 宿主: 兔 Polyclonal RB53642 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID)." in: Neuroscience, Vol. 341, pp. 42-51, (2016) (PubMed).
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: "Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID)." in: Neuroscience, Vol. 341, pp. 42-51, (2016) (PubMed).
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- KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
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别名
- BK channel
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背景
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Synonyms: SLO, BKTM, SLO1, MaxiK, SAKCA, mSLO1, KCa1.1, SLO-ALPHA, bA205K10.1, Calcium-activated potassium channel subunit alpha-1, BK channel, BKCA alpha, Calcium-activated potassium channel, subfamily M subunit alpha-1, K(VCA)alpha, Maxi K channel, Slowpoke homolog, Slo homolog, hSlo, KCNMA1, KCNMA
Background: Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
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基因ID
- 3778
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UniProt
- Q12791
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途径
- Regulation of Hormone Metabolic Process, Sensory Perception of Sound
抗原
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