Spindlin 1 抗体 (AA 3-100)
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北京 101111
Quick Overview for Spindlin 1 抗体 (AA 3-100) (ABIN672351)
抗原
See all Spindlin 1 (SPIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-100
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特异性
- There is 60 % sequence similarity with Spindlin 3, but the sequence is not continuous so the chance of bindin is low.
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Spindin 1
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亚型
- IgG
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anti-Spindlin 1 (SPIN1) (AA 1-262) antibody
SPIN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 1-262) antibodySPIN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (N-Term) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 111-160) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 179-228) antibodySPIN1 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 兔, 小鸡, 猴, 豚鼠, 斑马鱼, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Middle Region) antibodySPIN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Spindlin 1 (SPIN1)
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别名
- Spindlin 1
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背景
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Synonyms: SPIN, Spindlin-1, Ovarian cancer-related protein, Spindlin1, SPIN1, OCR
Background: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
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基因ID
- 10927
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UniProt
- Q9Y657
抗原
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