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LDLR 抗体 (AA 781-860)

Cited in 5+ publications. This anti-LDLR antibody is a 兔 多克隆 antibody detecting LDLR in WB, ELISA, FACS, IF (p) 和 IHC (p). Suitable for 人, 小鼠, 大鼠, Hamster 和 植物.
产品编号 ABIN672111
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LDLR 抗体 (AA 781-860) (ABIN672111)

抗原

See all LDLR 抗体
LDLR (Low Density Lipoprotein Receptor (LDLR))

适用

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人, 小鼠, 大鼠, Hamster, 植物

宿主

  • 84
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克隆类型

  • 72
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  • 1
多克隆

标记

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This LDLR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    AA 781-860

    交叉反应

    Hamster, 人, 小鼠, 植物, 大鼠

    交叉反应 (详细)

    Hamster

    预测反应

    Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human LDL-R

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Saxena, Kaur, Chandra: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).

    Kou, Han, Wang, Huang, He, Han, Zhou, Ye, Li: "Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters." in: Life sciences, Vol. 151, pp. 50-60, (2016) (PubMed).

    Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: "Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4627-35, (2016) (PubMed).

    Gow, Muirhead, Hay, Argyle: "Low-Density Lipoprotein Uptake Demonstrates a Hepatocyte Phenotype in the Dog, but Is Nonspecific." in: Stem cells and development, Vol. 25, Issue 1, pp. 90-100, (2015) (PubMed).

    Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 11, pp. 1373-81, (2014) (PubMed).

  • 抗原

    LDLR (Low Density Lipoprotein Receptor (LDLR))

    别名

    LDL receptor

    背景

    Synonyms: FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor, LDLR

    Background: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

    基因ID

    3949

    UniProt

    P01130

    途径

    Hepatitis C, Lipid Metabolism
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