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Neuropilin 1 抗体 (AA 851-923) (FITC)

This anti-Neuropilin 1 antibody is a 兔 多克隆 antibody detecting Neuropilin 1 in WB, IF (cc) 和 IF (p). Suitable for 人 和 大鼠.
产品编号 ABIN671998
发货至: 中国

Quick Overview for Neuropilin 1 抗体 (AA 851-923) (FITC) (ABIN671998)

抗原

See all Neuropilin 1 (NRP1) 抗体
Neuropilin 1 (NRP1)

适用

  • 115
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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 123
  • 31
  • 4
  • 3
  • 1

克隆类型

  • 116
  • 46
多克隆

标记

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  • 15
  • 4
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Neuropilin 1 antibody is conjugated to FITC

应用范围

  • 124
  • 69
  • 47
  • 40
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  • 28
  • 14
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  • 10
  • 4
  • 4
  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    • 4
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 851-923

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Sheep,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human neuropilin-1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Neuropilin 1 (NRP1)

    别名

    Neuropilin 1

    背景

    Synonyms: NP1, NRP, BDCA4, CD304, VEGF165R, Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, NRP1

    Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

    基因ID

    8829

    UniProt

    O14786

    途径

    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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