TMEM199 抗体 (AA 20-129)
Quick Overview for TMEM199 抗体 (AA 20-129) (ABIN6719657)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-129
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原理
- Anti-Transmembrane protein 199 TMEM199 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Transmembrane protein 199 TM Antibody (ABIN6719657). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TMEM199 recombinant protein (Position: E20-H129).
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亚型
- IgG
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anti-Transmembrane Protein 199 (TMEM199) antibody
TMEM199 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 199 (TMEM199) (N-Term) antibodyTMEM199 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 199 (TMEM199) (AA 46-75), (N-Term) antibodyTMEM199 适用: 人 WB 宿主: 兔 Polyclonal RB26669 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Calvo, P. L., Pagliardini, S., Baldi, M., Pucci, A., Sturiale, L., Garozzo, D., Vinciguerra, T., Barbera, C., Jaeken, J. Long-standing mild hypertransaminasaemia caused by congenital disorder of glycosylation (CDG) type IIx. J. Inherit. Metab. Dis. 31: S437-S440, 2008. 2. Jansen, J. C., Timal, S., van Scherpenzeel, M., Michelakakis, H., Vicogne, D., Ashikov, A., Moraitou, M., Hoischen, A., Huijben, K., Steenbergen, G., van den Boogert, M. A. W., Porta, F., and 14 others. TMEM199 deficiency is a disorder of Golgi homeostasis characterized by elevated aminotransferases, alkaline phosphatase, and cholesterol and abnormal glycosylation. Am. J. Hum. Genet. 98: 322-330, 2016. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TMEM199 (Transmembrane Protein 199 (TMEM199))
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别名
- TMEM199
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背景
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Synonyms: Transmembrane protein 199, TMEM199, C17orf32
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: TMEM199 encodes a protein homologous to the yeast V-ATPase assembly factor Vma12 and appears to be involved in Golgi homeostasis. The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) in some human cells. Defects in this gene are a cause of congenital disorder of glycosylation, type IIp. By genomic sequence analysis, the TMEM199 gene is mapped to chromosome 17q11.1.
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分子量
- 23 kDa
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基因ID
- 147007
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UniProt
- Q8N511
抗原
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