CLPX 抗体 (AA 337-574) (DyLight 550)
Quick Overview for CLPX 抗体 (AA 337-574) (DyLight 550) (ABIN7354570)
抗原
See all CLPX 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 337-574
-
原理
- Anti-Human CLPX DyLight® 550 conjugated Antibody
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Human CLPX DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human CLPX recombinant protein (Position: A337-E574).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Corydon, T. J., Wilsbech, M., Jespersgaard, C., Andresen, B. S., Borglum, A. D., Pedersen, S., Bolund, L., Gregersen, N., Bross, P. Human and mouse mitochondrial orthologs of bacterialClpX. Mammalian Genome 11: 899-905, 2000. 2. Kang, S. G., Dimitrova, M. N., Ortega, J., Ginsburg, A., Maurizi, M. R. Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX. J. Biol. Chem. 280: 35424-35432, 2005.
-
说明
-
Other applications have not been tested. Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
-
- CLPX (ClpX Caseinolytic Peptidase X (CLPX))
-
别名
- CLPX
-
背景
-
Synonyms: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX
Tissue Specificity: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.
Background: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
-
分子量
- 39 kDa
-
基因ID
- 10845
-
UniProt
- O76031
抗原
-