CCDC36 抗体 (AA 172-472)
Quick Overview for CCDC36 抗体 (AA 172-472) (ABIN6719645)
抗原
See all CCDC36 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 172-472
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原理
- Anti-CCDC36 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CCDC36 Antibody Picoband® (ABIN6719645). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CCDC36 recombinant protein (Position: E172-N472).
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 36 (CCDC36) (AA 11-592) antibody
CCDC36 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 36 (CCDC36) (AA 422-450), (C-Term) antibodyCCDC36 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB29727 unconjugated
anti-Coiled-Coil Domain Containing 36 (CCDC36) (AA 419-448), (C-Term) antibodyCCDC36 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Stanzione M., Baumann M., Papanikos F., Dereli I., Lange J., Ramlal A., Traenkner D., Shibuya H., de Massy B., Watanabe Y., Jasin M., Keeney S., Toth A. Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. Nat. Cell Biol. 18:1208-1220(2016) -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CCDC36 (Coiled-Coil Domain Containing 36 (CCDC36))
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别名
- CCDC36
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背景
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Synonyms: Interactor of HORMAD1 protein 1, Cancer/testis antigen 74, CT74, Coiled-coil domain-containing protein 36, CCDC36, IHO1
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: CCDC36, also known as CT74 (cancer/testis antigen 74), is a 584 amino acid protein that contains coiled-coil domains and is expressed as three alternatively spliced isoforms. The gene encoding CCDC36 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
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分子量
- 66 kDa
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基因ID
- 339834
抗原
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