TIMM17A 抗体
Quick Overview for TIMM17A 抗体 (ABIN6719637)
抗原
See all TIMM17A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Anti-TIMM17A Antibody Picoband®
-
序列
- LFSMIDCSMV QVRGKED
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-TIMM17A Antibody Picoband® (ABIN6719637). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TIMM17A, which shares 88.2% and 82.4% amino acid (aa) sequence identity with mouse and rat TIMM17A, respectively.
-
亚型
- IgG
-
-
anti-Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A) (C-Term) antibody
TIMM17A 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A) antibodyTIMM17A 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A) (AA 1-171) antibodyTIMM17A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A) (AA 1-171) antibodyTIMM17A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A) antibodyTIMM17A 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Bauer, M. F., Gempel, K., Reichert, A. S., Rappold, G. A., Lichtner, P., Gerbitz, K. D., Neupert, W., Brunner, M., Hofmann, S. Genetic and structural characterization of the human mitochondrial inner membrane translocase. J. Molec. Biol. 289: 69-82, 1999. 2. Bomer, U., Rassow, J., Zufall, N., Pfanner, N., Meijer, M., Maarse, A. C. The preprotein translocase of the inner mitochondrial membrane: evolutionary conservation of targeting and assembly of Tim17. J. Molec. Biol. 262: 389-395, 1996. 3. Iacovino, M., Granycome, C., Sembongi, H., Bokori-Brown, M., Butow, R. A., Holt, I. J., Bateman, J. M. The conserved translocase Tim17 prevents mitochondrial DNA loss. Hum. Molec. Genet. 18: 65-74, 2009. -
说明
-
Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))
-
别名
- TIMM17A
-
背景
-
Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17
Background: Mitochondrial import inner membrane translocase subunit Tim17-A is an enzyme that in humans is encoded by the TIMM17A gene. It is mapped to 1q32.1. TIM17 is a conserved suppressor of mtDNA instability, and overexpression of TIMM17A can prevent mtDNA loss in a human cellular model of mitochondrial disease.
-
分子量
- 18 kDa
-
基因ID
- 10440
-
UniProt
- Q99595
抗原
-
