TDRD3 抗体
Quick Overview for TDRD3 抗体 (ABIN6719636)
抗原
See all TDRD3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-TDRD3 Antibody Picoband®
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序列
- KPTNDNDEFE KQRTAAIAEV AKSKETK
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-TDRD3 Antibody Picoband® (ABIN6719636). Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human TDRD3, which shares 96.3% and 100% amino acid (aa) sequence identity with mouse and rat TDRD3, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunofluorescence, 2 μg/mL
1. Goulet, Boisvenue, S., Mokas, S., Mazroui, R., Cote, J. TDRD3, a novel tudor domain-containing protein, localizes to cytoplasmic stress granules. Hum. Molec. Genet. 17: 3055-3074, 2008. 2. Linder, B., Plottner, O., Kroiss, M., Hartmann, E., Laggerbauer, B., Meister, G., Keidel, E., Fischer, U. Tdrd3 is a novel stress granule-associated protein interacting with the fragile-X syndrome protein FMRP. Hum. Molec. Genet. 17: 3236-3246, 2008. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TDRD3 (Tudor Domain Containing 3 (TDRD3))
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别名
- TDRD3
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背景
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Synonyms: Tudor domain-containing protein 3, TDRD3
Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Background: Tudor domain-containing protein 3 is a protein that in humans is encoded by the TDRD3 gene. This gene is mapped to 13q21.2. It contains a Tudor domain and UBA protein domain and has three distinct Protein isoforms. TDRD3 is a multifunctional protein that acts as a transcriptional coactivator in the nucleus and as a scaffolding protein in cytoplasmic stress granules.
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分子量
- 65-73 kDa
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基因ID
- 81550
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UniProt
- Q9H7E2
抗原
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