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TDRD3 抗体

This anti-TDRD3 antibody is a 兔 多克隆 antibody detecting TDRD3 in WB, IF 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6719636
发货至: 中国

Quick Overview for TDRD3 抗体 (ABIN6719636)

抗原

See all TDRD3 抗体
TDRD3 (Tudor Domain Containing 3 (TDRD3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TDRD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 原理

    Anti-TDRD3 Antibody Picoband®

    序列

    KPTNDNDEFE KQRTAAIAEV AKSKETK

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TDRD3 Antibody Picoband® (ABIN6719636). Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human TDRD3, which shares 96.3% and 100% amino acid (aa) sequence identity with mouse and rat TDRD3, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunofluorescence, 2 μg/mL
    1. Goulet, Boisvenue, S., Mokas, S., Mazroui, R., Cote, J. TDRD3, a novel tudor domain-containing protein, localizes to cytoplasmic stress granules. Hum. Molec. Genet. 17: 3055-3074, 2008.  2. Linder, B., Plottner, O., Kroiss, M., Hartmann, E., Laggerbauer, B., Meister, G., Keidel, E., Fischer, U. Tdrd3 is a novel stress granule-associated protein interacting with the fragile-X syndrome protein FMRP. Hum. Molec. Genet. 17: 3236-3246, 2008.

    说明

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    TDRD3 (Tudor Domain Containing 3 (TDRD3))

    别名

    TDRD3

    背景

    Synonyms: Tudor domain-containing protein 3, TDRD3

    Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

    Background: Tudor domain-containing protein 3 is a protein that in humans is encoded by the TDRD3 gene. This gene is mapped to 13q21.2. It contains a Tudor domain and UBA protein domain and has three distinct Protein isoforms. TDRD3 is a multifunctional protein that acts as a transcriptional coactivator in the nucleus and as a scaffolding protein in cytoplasmic stress granules.

    分子量

    65-73 kDa

    基因ID

    81550

    UniProt

    Q9H7E2
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