RXFP2 抗体
Quick Overview for RXFP2 抗体 (ABIN6719634)
抗原
See all RXFP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-GPCR LGR8/RXFP2 Antibody Picoband®
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序列
- MIVFLVFKHL FSLRLITMFF LLHFIVLINV KDFALTQ
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GPCR LGR8/RXFP2 Antibody Picoband® (ABIN6719634). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GPCR LGR8.
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亚型
- IgG
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anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (AA 33-158) antibody
RXFP2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (Cytoplasmic Domain) antibodyRXFP2 适用: 人, 小鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (Extracellular Domain) antibodyRXFP2 适用: 人, 小鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (N-Term) antibodyRXFP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (Internal Region) antibodyRXFP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (AA 80-180) antibodyRXFP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (Internal Region) antibodyRXFP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Ars, E., Lo Giacco, D., Bassas, L., Nuti, F., Rajmil, O., Ruiz, P., Garat, J. M., Ruiz-Castane, E., Krausz, C. Further insights into the role of T222P variant of RXFP2 in non-syndromic cryptorchidism in two Mediterranean populations. Int. J. Androl. 34: 333-338, 2010. 2. Ferlin, A., Simonato, M., Bartoloni, L., Rizzo, G., Bettella, A., Dottorini, T., Dallapiccola, B., Foresta, C. The INSL3-LGR8/GREAT ligand-receptor pair in human cryptorchidism. J. Clin. Endocr. Metab. 88: 4273-4279, 2003. 3. Harris, R. M., Finlayson, C., Weiss, J., Fisher, L., Hurley, L., Barrett, T., Emge, D., Bathgate, R. A. D., Agoulnik, A. I., Jameson, J. L. A missense mutation in LRR8 of RXFP2 is associated with cryptorchidism. Mammalian Genome 21: 442-449, 2010. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RXFP2 (Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2))
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别名
- RXFP2
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背景
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Synonyms: Relaxin receptor 2, G-protein coupled receptor 106, G-protein coupled receptor affecting testicular descent, Leucine-rich repeat-containing G-protein coupled receptor 8, Relaxin family peptide receptor 2, RXFP2, GPR106, GREAT, LGR8
Tissue Specificity: Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.
Background: Relaxin/insulin-like family peptide receptor 2, also known as RXFP2, is a human G-protein coupled receptor. It is mapped to 13q13.1. This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 86 kDa
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途径
- cAMP Metabolic Process, Myometrial Relaxation and Contraction
抗原
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